Maria L Carlsson Selected Research

OSU 6162

1/2021	Open-label study with the monoamine stabilizer (-)-OSU6162 in myalgic encephalomyelitis/chronic fatigue syndrome.
12/2020	Effect of the monoaminergic stabiliser (-)-OSU6162 on mental fatigue following stroke or traumatic brain injury.
12/2018	Open study with (-)-OSU6162 in multiple sclerosis-related fatigue.
12/2013	The monoaminergic stabilizer (-)-OSU6162 reverses delay-dependent natural forgetting and improves memory impairment induced by scopolamine in mice.
10/2012	Placebo-controlled cross-over study of the monoaminergic stabiliser (-)-OSU6162 in mental fatigue following stroke or traumatic brain injury.
11/2011	II. In vitro evidence that (-)-OSU6162 and (+)-OSU6162 produce their behavioral effects through 5-HT2A serotonin and D2 dopamine receptors.
6/2005	The dopaminergic stabilizers (-)-OSU6162 and ACR16 reverse (+)-MK-801-induced social withdrawal in rats.

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Maria L Carlsson Research Topics

Disease

7	Schizophrenia (Dementia Praecox) 11/2011 - 07/2004
3	Mental Fatigue 12/2020 - 10/2012
2	Fatigue 01/2021 - 12/2018
2	Traumatic Brain Injuries (Traumatic Brain Injury) 12/2020 - 10/2012
2	Stroke (Strokes) 12/2020 - 10/2012
2	Obsessive-Compulsive Disorder (Disorder, Obsessive-Compulsive) 07/2008 - 11/2004
2	Psychotic Disorders (Schizoaffective Disorder) 01/2006 - 06/2005
1	Chronic Fatigue Syndrome (Myalgic Encephalomyelitis) 01/2021
1	Multiple Sclerosis 12/2018
1	Cognitive Dysfunction 12/2013
1	Memory Disorders (Memory Loss) 12/2013
1	Huntington Disease (Huntington's Disease) 11/2011
1	Parkinson Disease (Parkinson's Disease) 11/2011
1	Neurobehavioral Manifestations 09/2006
1	Autistic Disorder (Autism) 07/2004

Drug/Important Bio-Agent (IBA)

7	OSU 6162IBA 01/2021 - 06/2005
4	Dizocilpine Maleate (Dizocilpine)IBA 09/2006 - 07/2004
3	Glutamic Acid (Glutamate)FDA Link 07/2008 - 06/2005
3	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 09/2006 - 06/2005
2	Therapeutic UsesIBA 12/2020 - 12/2018
2	Pharmaceutical PreparationsIBA 12/2013 - 09/2006
2	Glutamine (L-Glutamine)FDA Link 07/2008 - 09/2006
2	N-Methylaspartate (NMDA)IBA 09/2006 - 07/2004
2	Dopamine (Intropin)FDA LinkGeneric 01/2006 - 06/2005
1	Scopolamine (Hyoscine)FDA Link 12/2013
1	Phencyclidine (Angel Dust)IBA 09/2006
1	Dopamine D2 Receptors (Dopamine D2 Receptor)IBA 01/2006
1	Antipsychotic Agents (Antipsychotics)IBA 06/2005
1	Haloperidol (Haldol)FDA LinkGeneric 06/2005
1	Amphetamine (Amfetamine)FDA LinkGeneric 06/2005
1	Dopamine Agonists (Dopamine Agonist)IBA 06/2005
1	Clozapine (Clozaril)FDA LinkGeneric 06/2005
1	Nicotine FDA Link 11/2004
1	ElementsIBA 07/2004

Therapy/Procedure

1	Self Medication 11/2004